Dracula
The vampire's durability approaches functional invulnerability under most combat scenarios. Conventional weapons pass through his mist form harmlessly, whilst physical attacks against his corporeal body regenerate within moments given adequate blood supply. Only specific countermeasures prove effective: wooden stakes through the heart, decapitation, direct sunlight, or holy symbols wielded with genuine faith.
This limited vulnerability profile creates asymmetric combat conditions. An opponent must possess both knowledge of vampiric weaknesses and the specific implements to exploit them. Random magical attacks, however powerful, simply fail to achieve permanent effect against an entity that has survived centuries of opposition.